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Product Details
MA5-17181
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1G4
Immunogen
Purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538652
Product Specific Information
MA5-17181 targets SRY in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.
Target Information
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: essential protein for sex determination in human males; sex determining region Y protein; sex-determining region on Y; Sex-determining region Y protein; Testis-determining factor; testis-determining factor on Y
Gene Aliases: SRXX1; SRXY1; SRY; TDF; TDY
UniProt ID: (Human) Q05066
Entrez Gene ID: (Human) 6736
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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