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产品信息
PA5-27982
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 100 and 387 of Human CD75
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545458
产品详细信息
Recommended positive controls: CD75 tansfected 293T cell.
Predicted reactivity: Mouse (87%), Rat (87%), Sheep (89%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha 2,6-ST 1; B-cell antigen CD75; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI
基因别名: SIAT1; ST6GAL1; ST6GalI; ST6N
UniProt ID: (Human) P15907
Entrez Gene ID: (Human) 6480
N-acetylneuraminate metabolic process
humoral immune response
oligosaccharide metabolic process
O-glycan processing
protein N-linked glycosylation via asparagine
positive regulation of mononuclear cell proliferation
response to ethanol
negative regulation of chemotaxis
sialylation
regulation of substrate adhesion-dependent cell spreading
protein sialylation
negative regulation of macrophage apoptotic process
