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STAM Antibody (PA5-144659) in ICC/IF
Immunocytochemistry analysis of STAM in SH-SY5Y cells. Cells were fixed in 4% paraformaldehyde for 30 minutes at room temperature, permeabilized with 0.1% Triton X-100 in PBS for 15 minutes, and then blocked with 2% BSA for 30 minutes at 37&(8)451;. Cells were incubated with STAM polyclonal antibody (Product # PA5-144659) with a dilution of 1:200 in 2% BSA overnight at 4 &(8)451;. Followed by secondary antibody Goat Anti-Rabbit IgG H&L (iFluor™ 488) at a dilution of 1:1,000. Nuclear DNA was labelled in blue with DAPI, beta tubulin (red) wa... View More
产品信息
PA5-144659
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within Human aa 30-55/540.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3091363
产品详细信息
Positive control: Siha, SHSY5Y, human kidney tissue, human colon tissue, Rat testis tissue.
Predicted band size: 59 kDa
Subcellular Location: Cytoplasm; Early endosome membrane.
靶标信息
STAM (Signal transducing adaptor molecule) is an adaptor molecule involved in downstream signaling pathways mediated by growth factors and cytokines. STAM also plays an important role in endocytosis, the JAK-STAT signaling pathway, and membrane trafficking. In humans, the gene encoding STAM is located on chromosome 10.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686J2352; HSE1 homolog; Signal transducing adapter molecule 1; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; STAM-1; STAT91
基因别名: RGD1564499; STAM; STAM-1; STAM1
UniProt ID: (Human) Q92783
Entrez Gene ID: (Human) 8027, (Rat) 498798
intracellular protein transport
autophagy
signal transduction
positive regulation of signal transduction
endosomal transport
multivesicular body assembly
negative regulation of epidermal growth factor receptor signaling pathway
positive regulation of exosomal secretion
regulation of extracellular exosome assembly
