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产品信息
PA5-121061
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4).
偶联物
形式
Liquid
浓度
1.27 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914633
产品详细信息
Positive test controls include: MCF7, HepG2, OVCAR3, PC-3. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein.
Immunogen sequence: KLHPPAHYPP ASSGVPMQTY PVQSHGGNYM GQSIHQVTVA QSYSLGPDQI GPLRSLPPNV NSSVTAQPAQ TSYLSTGQDT VSNPTYMNQN SNLQSATGTT AYTQQMGMSV DMSSYQNTTS NLPQLAGFPV TVPAHPVAQQ HTNYHQQPLL
靶标信息
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp564C047; HGNC:11358; Hrs binding protein; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; STAM-2; STAM-like protein containing SH3 and ITAM domains 2
基因别名: 1200004O12Rik; 5730456G07Rik; BB145015; HBP; STAM2; STAM2A; STAM2B
UniProt ID: (Human) O75886, (Rat) Q5XHY7, (Mouse) O88811
Entrez Gene ID: (Human) 10254, (Rat) 311030, (Mouse) 56324
