Invitrogen

STAP1 Polyclonal Antibody

查看其他6个STAP1抗体

抗体检测数据 (4)
高级验证 (1)

STAP1 Antibody in Immunocytochemistry (ICC/IF)

STAP1 Antibody in Immunocytochemistry (ICC/IF)

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STAP1 Antibody (PA5-58427) in ICC/IF

Immunofluorecent analysis of STAP1 in human cell line A-431 using STAP1 Polyclonal Antibody (Product # PA5-58427). Staining shows localization to nucleoplasm and vesicles.

STAP1 Antibody in Immunocytochemistry (ICC/IF)

STAP1 Antibody in Immunohistochemistry (IHC)

STAP1 Antibody in Immunohistochemistry (IHC)

STAP1 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

STAP1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorecent analysis of STAP1 in human cell line A-431 using STAP1 Polyclonal Antibody (Product # PA5-58427). Staining shows localization to nucleoplasm and vesicles.

STAP1 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of STAP1 in human lymph node and cerebral cortex tissues using STAP1 Polyclonal Antibody (Product # PA5-58427). Corresponding STAP1 RNA-seq data are presented for the same tissues.

STAP1 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of STAP1 in human cerebral cortex using STAP1 Polyclonal Antibody (Product # PA5-58427) shows low expression as expected.

STAP1 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of STAP1 in human lymph node using STAP1 Polyclonal Antibody (Product # PA5-58427) shows high expression.

STAP1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of STAP1 demonstrates antibody specificity. Immunohistochemical analysis of STAP1 using anti-STAP1 Polyclonal Antibody (Product # PA5-58427), shows significant staining of STAP1 in human lymph node and shows minimal or weak staining in human cerebral cortex tissues. The relative expression levels of STAP1 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-58427

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

-

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human STAP1. Recombinant protein control fragment (Product #RP-96503).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2647993

产品详细信息

Immunogen sequence: ESGEEWRGFI LTVTELSVPQ NVSLLPGQVI KLHEVLEREK KRRIETEQST SVEKEKEPTE DYVDVLNPMP ACFYTVSRKE ATEMLQK

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.

靶标信息

The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BCR downstream-signaling protein 1; Docking protein BRDG1; Signal-transducing adaptor protein 1; STAP-1; Stem cell adaptor protein 1

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基因别名: BRDG1; STAP-1; STAP1

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UniProt ID: (Human) Q9ULZ2

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Entrez Gene ID: (Human) 26228

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phosphotyrosine binding transmembrane receptor protein tyrosine kinase adaptor activity SH3/SH2 adaptor activity macrophage colony-stimulating factor receptor binding protein binding phospholipid binding protein kinase binding scaffold/adaptor protein

transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of gene expression negative regulation of macrophage chemotaxis negative regulation of phosphorylation positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation positive regulation of non-membrane spanning protein tyrosine kinase activity negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity positive regulation of actin cytoskeleton reorganization