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Recommended positive controls: human STC1-transfected 293T.
Predicted reactivity: Mouse (97%), Rat (96%), Pig (92%), Rhesus Monkey (99%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Stanniocalcin-1; STC-1
基因别名: STC; STC1
UniProt ID: (Human) P52823, (Mouse) O55183
Entrez Gene ID: (Human) 6781, (Mouse) 20855