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产品信息
PA5-56326
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648023
产品详细信息
Immunogen sequence: SLLRHSQESN SLQQQSWYGT FLQDLMAVIQ AYFACTFNLE RSQTSDSLQV FQEAANLFLD LLGKLLAQPD DSEQTLRRDS LMCFTVLCE
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%.
靶标信息
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fused homolog; Serine/threonine-protein kinase 36; STK36; testicular tissue protein Li 188
基因别名: FU; KIAA1278; STK36
UniProt ID: (Human) Q9NRP7
Entrez Gene ID: (Human) 27148
epithelial cilium movement
protein phosphorylation
positive regulation of hh target transcription factor activity
brain development
post-embryonic development
cilium assembly
positive regulation of smoothened signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
