Invitrogen

STRN Polyclonal Antibody

STRN Antibody in Immunocytochemistry (ICC/IF)

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STRN Antibody (PA5-99830) in ICC/IF

Immunocytochemistry analysis of STRN in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with STRN polyclonal antibody (Product # PA5-99830) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).

STRN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-99830

应用

建议稀释比

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免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human STRN(Accession O43815), corresponding to amino acid residues L109-R159.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2818763

产品详细信息

Antibody detects endogenous levels of total STRN.

靶标信息

Striatin is found in all mammalian cells assayed and may be involved in vesicular transport, dendrite growth, and cellular signaling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also includes SG2NA and Zinedin. This antibody does not cross-react with SG2NA.

仅用于科研。不用于诊断过程。未经明确授权不得转售。