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产品信息
PA5-51535
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648055
产品详细信息
Immunogen sequence: RLEPAIQKFI KIVIPTDLER LRKHQINIEK YQRCRIWDKL HEEHINAGRT VQQLRSNIRE IEKLCLKVRK DDLVLLKRMI DPVKEEASAA TAEFLQLHLE SVEELKKQFN DEETLLQPPL TRSMTVGGAF HTTEAEASSQ SLTQ
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 86%.
靶标信息
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)
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