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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Syntaxin-7; Syntaxin7
基因别名: AI315064; AI317144; AW107239; STX7; Syn7
UniProt ID: (Human) O15400, (Rat) O70257
Entrez Gene ID: (Human) 8417, (Rat) 60466, (Mouse) 53331