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产品信息
PA5-22051
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 138 and 416 of SUCLA2 (Uniprot ID#Q9P2R7)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11154074
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain.
Predicted reactivity: Mouse (90%), Rat (88%), Zebrafish (81%), Xenopus laevis (85%), Chicken (90%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; ATP-specific succinyl-CoA synthetase, beta subunit; mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta; renal carcinoma antigen NY-REN-39; RP11-528D24.2; SCS-betaA; SCSbetaA; succinate--CoA ligase (ADP-forming); Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; succinate-CoA ligase beta subunit; succinate-CoA ligase, ADP-forming, beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase beta-A chain
基因别名: 4930547K18Rik; A-BETA; MTDPS5; SCS-betaA; SUCLA2
UniProt ID: (Human) Q9P2R7, (Mouse) Q9Z2I9
Entrez Gene ID: (Human) 8803, (Mouse) 20916
succinate-CoA ligase (ADP-forming) activity
protein binding
ATP binding
metal ion binding
nucleotide binding
catalytic activity
acyl-CoA ligase activity
succinate-CoA ligase activity
3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity
fatty acid ligase activity
ligase activity
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
benzoyl acetate-CoA ligase activity
2,4-dichlorobenzoate-CoA ligase activity
pivalate-CoA ligase activity
cyclopropanecarboxylate-CoA ligase activity
adipate-CoA ligase activity
citronellyl-CoA ligase activity
mentha-1,3-dione-CoA ligase activity
thiophene-2-carboxylate-CoA ligase activity
2,4,4-trimethylpentanoate-CoA ligase activity
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
branched-chain acyl-CoA synthetase (ADP-forming) activity
aryl-CoA synthetase (ADP-forming) activity
3-hydroxypropionyl-CoA synthetase activity
perillic acid:CoA ligase (ADP-forming) activity
perillic acid:CoA ligase (AMP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
pristanate-CoA ligase activity
malonyl-CoA synthetase activity
ligase
