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Positive Samples: U-251MG, HepG2, A-549, Mouse thymus, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat liver
Immunogen sequence: CSYTASRQHL YVDKNTKIIC QGFTGKQGTF HSQQALEYGT KLVGGTTPGK GGQTHLGLPV FNTVKEAKEQ TGATASVIYV PPPFAAAAIN EAIEAEIPLV VCITEGIPQQ DMVRVKHKLL RQEKTRLIGP NCPGVINPGE CKIGIMPGHI HKKGRIGIVS RSGTLTYEAV HQTTQVGLGQ SLCVGIGGDP FNGTDFIDCL EIFLNDSATE GIILIGEIGG NAEENAAEFL KQHNSGPNSK PVVSFIAGLT APPGRRMGHA GAIIAGGKGG AKEKISALQS AGVVVSMSPA QLGTTIYKEF EKRKML
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SCS-alpha; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase, alpha subunit; succinate-CoA ligase, GDP-forming alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase subunit alpha
基因别名: 1500000I01Rik; GALPHA; MTDPS9; SUCLA1; SUCLG1
UniProt ID: (Human) P53597, (Rat) P13086, (Mouse) Q9WUM5
Entrez Gene ID: (Human) 8802, (Rat) 114597, (Mouse) 56451