Invitrogen

SUFU Polyclonal Antibody

查看其他15个SUFU抗体

抗体检测数据 (5)

SUFU Antibody in Immunocytochemistry (ICC/IF)

SUFU Antibody in Immunocytochemistry (ICC/IF)

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SUFU Antibody (PA5-109247) in ICC/IF

Immunofluorescent analysis of SUFU in SH-SY-5Y cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with SUFU polyclonal antibody (Product # PA5-109247), followed by DAPI (blue).

SUFU Antibody in Immunocytochemistry (ICC/IF)

SUFU Antibody in Immunocytochemistry (ICC/IF)

SUFU Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SUFU Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SUFU Antibody in Western Blot (WB)

Product Image Gallery

SUFU Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of SUFU in SH-SY-5Y cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with SUFU polyclonal antibody (Product # PA5-109247), followed by DAPI (blue).

SUFU Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of SUFU in A549 cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with SUFU polyclonal antibody (Product # PA5-109247), followed by DAPI (blue).

SUFU Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of SUFU in paraffin-embedded human colon cancer tissue. Samples were incubated with SUFU polyclonal antibody (Product # PA5-109247), and followed by hematoxylin.

SUFU Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of SUFU in paraffin-embedded human kidney tissue. Samples were incubated with SUFU polyclonal antibody (Product # PA5-109247), and followed by hematoxylin.

SUFU Antibody in Western Blot (WB) — Western blot analysis of SUFU in 293 cell lysate. Samples were incubated with SUFU polyclonal antibody (Product # PA5-109247), at a dilution of 1:500.

产品信息

PA5-109247

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

免疫细胞化学 (ICC/IF)

1:50-1:200

-

流式细胞分析 (Flow)

1 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein within Human SUFU aa 33-260

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol, 0.2% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles, store in dark

运输条件

Ambient (domestic); Wet ice (international)

AB_2854658

产品详细信息

Positive Control: 293, SH-SY-5Y, A549, human kidney tissue, human colon cancer tissue.

靶标信息

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; RP11-47A8.1; SUFUH; Suppressor of fused homolog

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基因别名: PRO1280; SUFU; SUFUH; SUFUXL; UNQ650/PRO1280

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UniProt ID: (Human) Q9UMX1

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Entrez Gene ID: (Human) 51684

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transcription corepressor activity signal transducer activity protein binding beta-catenin binding transcription factor binding protein kinase binding scaffold/adaptor protein

negative regulation of transcription from RNA polymerase II promoter skeletal system development neural tube closure heart looping ventricular septum development regulation of transcription, DNA-templated proteolysis signal transduction multicellular organism development smoothened signaling pathway involved in ventral spinal cord interneuron specification smoothened signaling pathway involved in spinal cord motor neuron cell fate specification aorta development negative regulation of transcription factor import into nucleus cytoplasmic sequestering of transcription factor negative regulation of sequence-specific DNA binding transcription factor activity skin development negative regulation of osteoblast differentiation negative regulation of smoothened signaling pathway coronary vasculature development negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process