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Invitrogen
SULF2 Polyclonal Antibody
Product Details
PA5-43331
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human SULF2 (aa 801-850).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2606833
Product Specific Information
Peptide sequence: DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW
Sequence homology: Cow: 79%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 100%
Target Information
Heparan sulfate 6-O-endosulfatases, such as Sulfatase 2, selectively remove 6-O-sulfate groups from heparan sulfate. Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Arylsulfatase; DKFZp313E091; Extracellular sulfatase Sulf-2; FLJ44488; FLJ90554; hSulf-2; MGC126411; N-acetylglucosamine-6-sulfatase; OTTHUMP00000031223; RP5-1049G16.1
Gene Aliases: HSULF-2; KIAA1247; SULF2; UNQ559/PRO1120
UniProt ID: (Human) Q8IWU5
Entrez Gene ID: (Human) 55959
kidney development
chondrocyte development
glomerular filtration
response to wounding
positive regulation of vascular endothelial growth factor production
esophagus smooth muscle contraction
positive regulation of Wnt signaling pathway
heparan sulfate proteoglycan metabolic process
glomerular basement membrane development
positive regulation of catenin import into nucleus
glial cell-derived neurotrophic factor receptor signaling pathway
negative regulation of fibroblast growth factor receptor signaling pathway
embryonic skeletal system development
cartilage development
bone development
innervation
positive regulation of canonical Wnt signaling pathway
liver regeneration
regulation of hepatocyte proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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