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Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Rat, Bovine (100%) Opossum (93%) Turkey, Chicken, Xenopus (87%).
This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene uses multiple polyadenylation sites, resulting in transcript length variation. The existence of alternatively spliced transcript variants has been suggested, but their validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: surface 4 integral membrane protein; Surfeit locus protein 4
基因别名: AL033340; AL033373; ERV29; SURF-4; SURF4
UniProt ID: (Human) O15260, (Bovine) A7YY49, (Mouse) Q64310
Entrez Gene ID: (Human) 6836, (Bovine) 526045, (Mouse) 20932, (Rat) 619346