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SVCT2/SLC23A2 (extracellular) Antibody (AST-022-200UL) in IHC (F)
Expression of SVCT2 in mouse hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-SVCT2/SLC23A2 (extracellular) Antibody (#AST-022), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. SVCT2 staining (green) in CA1 hippocampal region is detected in axonal processes (arrows), with the highest density surrounding the pyramidal layer (P). Cell nuclei are stained... View More
Product Details
AST-022-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EITVANGTAELLEH, corresponding to amino acid residues 191-204 of mouse SVCT2, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSVCT2; mSVCT2; Na(+)/L-ascorbic acid transporter 2; Nucleobase transporter-like 1 protein; sodium-coupled ascorbic acid transporter 2; Sodium-dependent vitamin C transporter 2; sodium-dependent vitamin C transporter-2; solute carrier family 23 (ascorbic acid transporter), member 2; solute carrier family 23 (nucleobase transporters), member 1; solute carrier family 23 (nucleobase transporters), member 2; Solute carrier family 23 member 2; SVCT-2; testicular secretory protein Li 48; Yolk sac permease-like molecule 2
Gene Aliases: AI844736; hSVCT2; KIAA0238; mKIAA0238; NBTL1; SLC23A1; SLC23A2; SVCT2; YSPL2; YSPL3
UniProt ID: (Human) Q9UGH3, (Mouse) Q9EPR4, (Rat) Q9WTW8
Entrez Gene ID: (Human) 9962, (Mouse) 54338, (Rat) 50622
L-ascorbate:sodium symporter activity
sodium-dependent multivitamin transmembrane transporter activity
nucleobase transmembrane transporter activity
L-ascorbic acid transporter activity
sodium-dependent L-ascorbate transmembrane transporter activity
transporter activity
symporter activity
transporter
nucleobase-containing compound metabolic process
response to oxidative stress
nucleobase transport
L-ascorbic acid transport
molecular hydrogen transport
L-ascorbic acid metabolic process
vitamin transmembrane transport
sodium ion transmembrane transport
transepithelial L-ascorbic acid transport
transport
ion transport
sodium ion transport
carbohydrate transmembrane transport
transmembrane transport
anion transmembrane transport
organic acid transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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