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SVOPL (putative transporter SVOPL), also known as SV2-related protein-like, is a 492 amino acid multi-pass membrane protein belonging to the major facilitator superfamily. SVOPL is a paralog to synaptic vesicle protein (SVOP) that exists as two alternatively spliced isoforms. The gene encoding SVOPL maps to human chromosome 7q34. Chromosome 7 is approximately 158 milllion bases long, encodes over 1,000 genes and makes up approximately 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Deletions of portions of the q arm of chromosome 7 are linked to myeloid disorders, including acute myelogenous leukemia and myelodysplasia.
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蛋白别名: Putative transporter SVOPL; similar to RIKEN cDNA 9430071P14 gene; SV2 related protein homolog-like; SV2-related protein-like; SVOP-like; SVOP-like protein
基因别名: 9430071P14Rik; SVOPL
UniProt ID: (Human) Q8N434, (Mouse) Q6PDF3
Entrez Gene ID: (Rat) 500085, (Human) 136306, (Mouse) 320590