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A suggested positive control is rat brain tissue lysate.
PA5-20876 can be used with blocking peptide PEP-0990.
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p29; RP3-333H23.3; Synaptogyrin-1
基因别名: p29; R75468; SYNGR1; Syngr1b
UniProt ID: (Human) O43759, (Mouse) O55100, (Rat) Q62876
Entrez Gene ID: (Human) 9145, (Mouse) 20972, (Rat) 29205