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产品信息
PA5-51471
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648143
产品详细信息
Immunogen sequence: NGRVDYLVTE EEINLTRGPS GLGFNIVGGT DQQYVSNDSG IYVSRIKENG AAALDGRLQE GDKILSVNGQ DLKNLLHQDA VDLFRNAGYA VSLRVQHRLQ VQNGPIGHRG EG
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
靶标信息
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: activin receptor interacting protein 2; activin receptor interacting protein 5; Activin receptor-interacting protein 2; activin receptor-interacting protein 2a; Activin receptor-interacting protein 4; Mitochondrial outer membrane protein 25; outer membrane protein 25; Synaptojanin-2-binding protein; synj2bp
基因别名: AA409442; ActRIP4; ARIP2; ARIP2a; D12Wsu118e; OMP25; SYNJ2BP
UniProt ID: (Human) P57105, (Mouse) Q9D6K5
Entrez Gene ID: (Human) 55333, (Mouse) 24071
negative regulation of endothelial cell proliferation
positive regulation of receptor internalization
protein targeting
Rho protein signal transduction
regulation of Notch signaling pathway
negative regulation of endothelial cell migration
negative regulation of angiogenesis
negative regulation of activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
intracellular distribution of mitochondria
negative regulation of ERK1 and ERK2 cascade
negative regulation of sprouting angiogenesis
positive regulation of protein localization to cell surface
cytoplasm organization
regulation of endocytosis
