Invitrogen

SYNM Polyclonal Antibody

SYNM Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SYNM Antibody (PA5-59053) in IHC (P)

Immunohistochemical analysis of SYNM in human skeletal muscle using SYNM Polyclonal Antibody (Product # PA5-59053) shows strong cytoplasmic positivity in myocytes.

SYNM Antibody in Immunohistochemistry (IHC)

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SYNM Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of SYNM demonstrates antibody specificity. Immunohistochemical analysis of SYNM using anti-SYNM Polyclonal Antibody (Product # PA5-59053), shows significant staining of SYNM in human smooth muscle and shows minimal or weak staining in human liver tissues. The relative expression levels of SYNM within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-59053

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:1,000-1:2,500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human SYNM. Recombinant protein control fragment (Product #RP-102883).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.40 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2648144

产品详细信息

Immunogen sequence: FLGSGYSSSA TTQQENSYGK AVSSQTNVRT FSPTYGLLRN TEAQVKTFPD RPKAGDTREV PVYIGEDSTI ARESYRDRRD KVAAGASEST RSNE

Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 53%.

靶标信息

Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。