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SYTL2 Antibody (PA5-24730) in IHC (P)
Immunohistochemistry analysis of SYTL2 in formalin fixed and paraffin embedded brain tissue. Samples were incubated with SYTL2 polyclonal antibody (Product # PA5-24730) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-24730
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 840-868 amino acids from the central region of human SYTL2
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2542230
靶标信息
SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Breast cancer-associated antigen SGA-72M; chromosome 11 synaptotagmin; Exophilin-4; protein phosphatase 1, regulatory subunit 151; synaptotagmin-like 2; Synaptotagmin-like protein 2
基因别名: CHR11SYT; EXO4; KIAA1597; PPP1R151; SGA72M; SLP2; SLP2A; SYTL2
UniProt ID: (Human) Q9HCH5
Entrez Gene ID: (Human) 54843
intracellular protein transport
exocytosis
vesicle docking involved in exocytosis
vesicle fusion
negative regulation of phosphatase activity
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
positive regulation of mucus secretion
protein localization to plasma membrane
