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Semaphorin 7A (SEMA7A) (extracellular) Antibody (ASR-077-200UL) in WB
Western blot analysis of human Jurkat T-cell leukemia cell line lysate: - 1. Anti-Semaphorin 7A (SEMA7A) (extracellular) Antibody (#ASR-077), (1:400). 2. Anti-Semaphorin 7A (SEMA7A) (extracellular) Antibody , preincubated with Semaphorin 7A/SEMA7A (extracellular) Blocking Peptide (#BLP-SR077).
产品信息
ASR-077-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RKQEYNGKIPRFRR, corresponding to amino acid residues 190-203 of mouse SEMA7A, Extracellular
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD108; CDw108; H-Sema K1; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; John-Milton-Hargen human blood group Ag; MGC126692; MGC126696; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; Sema K1; Sema L; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; Semaphorin-7A; Semaphorin-K1; Semaphorin-L
基因别名: 2900057C09Rik; CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; M-Sema-L; SEMA7A; SEMAK1; SEMAL; Semk1
UniProt ID: (Human) O75326, (Mouse) Q9QUR8
Entrez Gene ID: (Human) 8482, (Mouse) 20361, (Rat) 315711
osteoblast differentiation
neural crest cell migration
inflammatory response
immune response
integrin-mediated signaling pathway
olfactory lobe development
positive regulation of cell migration
positive regulation of axon extension
axon extension
negative regulation of axon extension involved in axon guidance
regulation of inflammatory response
negative chemotaxis
positive regulation of macrophage cytokine production
positive regulation of ERK1 and ERK2 cascade
semaphorin-plexin signaling pathway
positive regulation of protein phosphorylation
multicellular organism development
nervous system development
cell differentiation
neuron projection development
