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Serum Amyloid P Antibody (PA5-24171) in IHC (P)
Immunohistochemistry analysis of Serum Amyloid P in formalin fixed and paraffin embedded human hepatocarcinoma. Samples were incubated with Serum Amyloid P polyclonal antibody (Product # PA5-24171) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-24171
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541671
靶标信息
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 9.5S alpha-1-glycoprotein; epididymis secretory sperm binding protein Li 92n; MGC88159; Pentaxin related; pentaxin-related; Pentraxin 2; pentraxin-2; pentraxin-related; PTX 2; SAMP; SAP; Serum amyloid P-component; Serum amyloid P-component(1-203)
基因别名: APCS; HEL-S-92n; PTX2; SAP
UniProt ID: (Human) P02743
Entrez Gene ID: (Human) 325
negative regulation of acute inflammatory response
protein folding
acute-phase response
cellular protein metabolic process
negative regulation by host of viral exo-alpha-sialidase activity
negative regulation by host of viral glycoprotein metabolic process
innate immune response
negative regulation of monocyte differentiation
negative regulation of viral entry into host cell
negative regulation of viral process
chaperone-mediated protein complex assembly
negative regulation of wound healing
negative regulation of exo-alpha-sialidase activity
negative regulation of glycoprotein metabolic process
