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Positive Control: Raji, NIH-3T3, JC, BCL-1, C2C12
Predicted Reactivity: Rat (100%), Japanese Medaka (98%), Xenopus laevis (98%), Pig (100%), Chicken (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin alpha 1; Actin, alpha skeletal muscle; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; Alpha-actin-1; Alpha-actin-2; alpha-cardiac actin; Cell growth-inhibiting gene 46 protein; nemaline myopathy type 3; smooth muscle alpha-actin
基因别名: 0610041G09Rik; a-SMA; AA959943; AAT6; ACTA; Acta-2; ACTA1; ACTA2; Acts; ACTSA; Actsk-1; ACTVS; alphaSMA; ASMA; CFTD; CFTD1; CFTDM; GIG46; MPFD; MYMY5; NEM1; NEM2; NEM3; SHPM; SMalphaA
UniProt ID: (Human) P68133, (Human) P62736, (Mouse) P68134, (Rat) P68136, (Rat) P62738, (Mouse) P62737
Entrez Gene ID: (Human) 58, (Human) 59, (Mouse) 11459, (Rat) 29437, (Rat) 81633, (Mouse) 11475