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SmcHD1 Antibody (A302-871A) in IHC (P)
Detection of human SmcHD1 by immunohistochemistry. Sample: FFPE section of human testicular seminoma (left) and non-small cell lung cancer (right). Antibody: Affinity purified rabbit anti-SmcHD1 (Product # A302-871A) (Lot 1) used at a dilution of 1:200 (1 µg/mL). Detection: Vector Laboratories ImmPACT NovaRED Peroxidase Substrate.
Product Details
A302-871A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 250 and 300 of Human Structural Maintenance of Chromosomes Flexible Hinge Domain containing 1,.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SMC hinge domain-containing protein 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
Gene Aliases: KIAA0650; SMCHD1
UniProt ID: (Human) Q9H6Q2
Entrez Gene ID: (Human) 23347
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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