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Sorbitol Dehydrogenase Antibody (PA5-120389) in WB
Western blot analysis of Sorbitol Dehydrogenase in extracts of various cell lines. Samples were incubated with Sorbitol Dehydrogenase Polyclonal antibody (Product # PA5-120389) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-120389
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-357 of human Sorbitol Dehydrogenase (NP_0030952)
偶联物
形式
Liquid
浓度
1.773 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913961
产品详细信息
Positive test controls include: Mouse testis, Mouse kidney, Mouse liver, Rat liver. The target is usually found in the following locations: Cell projection, Mitochondrion membrane, Peripheral membrane protein, cilium, flagellum.
Immunogen sequence: MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGNL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP
靶标信息
Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase
基因别名: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1
UniProt ID: (Human) Q00796, (Rat) P27867, (Mouse) Q64442
Entrez Gene ID: (Human) 6652, (Rat) 24788, (Mouse) 20322
glucose metabolic process
sorbitol catabolic process
response to osmotic stress
response to hormone
glucuronate catabolic process to xylulose 5-phosphate
sperm motility
response to nutrient levels
response to drug
fructose biosynthetic process
response to cadmium ion
response to copper ion
L-xylitol catabolic process
L-xylitol metabolic process
oxidation-reduction process
sorbitol metabolic process
