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Spinophilin Antibody (OSS00399W-100UL) in IHC (P)
IHC-P on paraffin sections of rat olfactory bulbs. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela ... View More
产品信息
OSS00399W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from aa region 450-500 of human Spinophilin conjugated to blue carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and rat.
Specificity of this antibody: Spinophilin.
靶标信息
interacts with protein phosphatase 1 and actin filaments; involved in regulation of synaptic transmission.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: neurabin 2; neurabin II; Neurabin-2; Neurabin-II; Neural tissue-specific F-actin-binding protein II; nuerabin 2; p130; PP1bp134; Protein phosphatase 1 regulatory subunit 9B; protein phosphatase 1, regulatory (inhibitor) subunit 9B; protein phosphatase 1, regulatory subunit 9B; protein phosphatase 1, regulatory subunit 9B, spinophilin; Spinophilin
基因别名: Neb2; PPP1R6; PPP1R9; PPP1R9B; SPINO; SPL; Spn
UniProt ID: (Human) Q96SB3, (Rat) O35274, (Mouse) Q6R891
Entrez Gene ID: (Human) 84687, (Rat) 84686, (Mouse) 217124
regulation of protein phosphorylation
actin filament organization
dendrite development
cell migration
calcium-mediated signaling
negative regulation of cell growth
regulation of cell proliferation
filopodium assembly
modulation of synaptic transmission
cellular response to morphine
regulation of opioid receptor signaling pathway
protein phosphorylation
multicellular organism development
nervous system development
actin cytoskeleton organization
cell differentiation
negative regulation of phosphoprotein phosphatase activity
cellular response to light stimulus
positive regulation of establishment of protein localization to plasma membrane
protein localization to actin cytoskeleton
positive regulation of cellular protein localization
regulation of cell growth by extracellular stimulus
cell cycle arrest
regulation of exit from mitosis
RNA splicing
neuron projection development
negative regulation of catalytic activity
