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Synaptojanin1 Antibody (OSS00431W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse olfactory bulbs. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candel... View More
产品信息
OSS00431W-100UL
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from human Synaptojanin1 conjugated to blue carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat, mouse, marmoset.
Specificity of this antibody: Synaptojanin1.
靶标信息
Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: inositol 5'-phosphatase (synaptojanin 1); inositol polyphosphate-5-phosphatase G; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; Synaptojanin-1; synaptojanin-1, polyphosphoinositide phosphatase
基因别名: A930006D20Rik; AA675315; INPP5G; KIAA0910; mKIAA0910; PARK20; SYNJ1
UniProt ID: (Human) O43426, (Rat) Q62910
Entrez Gene ID: (Human) 8867, (Rat) 85238, (Mouse) 104015
nucleotide binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
nucleic acid binding
protein binding
protein C-terminus binding
SH3 domain binding
protein complex binding
phosphoric ester hydrolase activity
phosphatase
phosphatidylinositol biosynthetic process
neurotransmitter transport
learning
synaptic vesicle priming
synaptic vesicle uncoating
phosphatidylinositol-3-phosphate biosynthetic process
inositol phosphate metabolic process
phosphatidylinositol metabolic process
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
synaptic vesicle endocytosis
synaptic vesicle transport
positive regulation of endosome organization
brain development
positive regulation of gliogenesis
response to retinoic acid
response to cytokine
positive regulation of receptor-mediated endocytosis
dephosphorylation
phosphatidylinositol-mediated signaling
positive regulation of synaptic vesicle recycling
