Invitrogen

Syntaxin 1 Monoclonal Antibody (SP6), FITC

产品信息

MA5-17614

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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流式细胞分析 (Flow)

0.5 µg/1x10^6 cells

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SP6

抗原

Human Syntaxin

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein G

保存液

PBS with 4-5mg/mL BSA

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

运输条件

Ambient (domestic); Wet ice (international)

AB_2539004

产品详细信息

MA5-17614 targets Syntaxin-1 in FACS applications and shows reactivity with Human, Mouse, and Rat samples.

The MA5-17614 immunogen is human Syntaxin.

靶标信息

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Product References

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.

Nature immunology

Huang LR,Wohlleber D,Reisinger F,Jenne CN,Cheng RL,Abdullah Z,Schildberg FA,Odenthal M,Dienes HP,van Rooijen N,Schmitt E,Garbi N,Croft M,Kurts C,Kubes P,Protzer U,Heikenwalder M,Knolle PA

MA5-17614 was used in immunohistochemistry to study the local expansion of CD8-positice T-cells in intrahepatic myeloid-cell aggregates and the implications for chronic hepatic viral infection immunotherapy

Sat Jun 01 00:00:00 UTC 2013

Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation.

Cancer biotherapy & radiopharmaceuticals

Revskaya E,Chu P,Howell RC,Schweitzer AD,Bryan RA,Harris M,Gerfen G,Jiang Z,Jandl T,Kim K,Ting LM,Sellers RS,Dadachova E,Casadevall A

MA5-17614 was used in immunohistochemistry to study the ability of oral administration of mushrooms containing melanin to protect the gut against ionizing radiation

Thu Nov 01 00:00:00 UTC 2012

生物信息学

蛋白别名: Neuron-specific antigen HPC-1; P35A; STX1B; STX1B1; STX1B2; STXA1; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; Syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2

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基因别名: HPC-1; P35-1; Sap; STX1; STX1A; SYN1A

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UniProt ID: (Human) Q16623, (Mouse) O35526, (Rat) P32851

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Entrez Gene ID: (Human) 6804, (Mouse) 20907, (Rat) 116470

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功能