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Antibody detects endogenous levels of total STX6.
Syntaxin 6 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HGNC:11441; Syn6; Syntaxin-6
基因别名: 2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; STX6
UniProt ID: (Human) O43752, (Mouse) Q9JKK1, (Rat) Q63635
Entrez Gene ID: (Human) 10228, (Mouse) 58244, (Rat) 60562