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T Antibody (H00006862-D01P) in WB
Western Blot analysis of T expression in transfected 293T cell line (H00006862-T01) by T MaxPab polyclonal antibody.
Lane 1: T transfected lysate(41.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: T transfected lysate(41.10 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00006862-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
T (AAH98425.1, 1 a.a. approximately 377 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MSSPGTESAG KSLQYRVDHL LSAVENELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVAADNH RWKYVNGEWV PGGKPEPQAP SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGDPQR MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERSDHKEMM EEPGDSQQPG YSQSYSDNSP ACLSMLQSHD NWSSLGMPAH PSMLPVSHNA SPPTSSSQYP SLWSVSNGAV TPGSQAAAVS NGLGAQFFRG SPAHYTPLTH PVSAPSSSGS PLYEGAAAAT DIVDSQYDAA AQGRLIASWT PVSPPSM
靶标信息
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brachyury protein; Protein T; RP11-459F1.1; T brachyury homolog; T, brachyury homolog; T-box transcription factor T
基因别名: SAVA; T; TBXT; TFT
UniProt ID: (Human) O15178
Entrez Gene ID: (Human) 6862
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Rel homology transcription factor
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
somitogenesis
neural plate morphogenesis
neural tube closure
heart morphogenesis
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription, DNA-templated
signal transduction
penetration of zona pellucida
mesoderm development
mesoderm migration involved in gastrulation
positive regulation of cell proliferation
anterior/posterior axis specification, embryo
notochord formation
signal transduction involved in regulation of gene expression
BMP signaling pathway
post-anal tail morphogenesis
embryonic skeletal system development
canonical Wnt signaling pathway
bone morphogenesis
SMAD protein signal transduction
determination of heart left/right asymmetry
cellular response to retinoic acid
primitive streak formation
