Abnova

T Polyclonal Antibody, MaxPab™

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T Antibody in Western Blot (WB)

T Antibody in Western Blot (WB)

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T Antibody (H00006862-D03P) in WB

Western Blot analysis of T expression in transfected 293T cell line by T MaxPab polyclonal antibody. Lane 1: T transfected lysate(41.1 KDa). Lane 2: Non-transfected lysate. .

T Antibody in Western Blot (WB)

Product Image Gallery

T Antibody in Western Blot (WB) — Western Blot analysis of T expression in transfected 293T cell line by T MaxPab polyclonal antibody. Lane 1: T transfected lysate(41.1 KDa). Lane 2: Non-transfected lysate. .

产品信息

H00006862-D03P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

T (AAH98425.1, 1 a.a. approximately 377 a.a) full-length human protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MSSPGTESAG KSLQYRVDHL LSAVENELQA GSEKGDPTER ELRVGLEESE LWLRFKELTN EMIVTKNGRR MFPVLKVNVS GLDPNAMYSF LLDFVAADNH RWKYVNGEWV PGGKPEPQAP SCVYIHPDSP NFGAHWMKAP VSFSKVKLTN KLNGGGQIML NSLHKYEPRI HIVRVGDPQR MITSHCFPET QFIAVTAYQN EEITALKIKY NPFAKAFLDA KERSDHKEMM EEPGDSQQPG YSQSYSDNSP ACLSMLQSHD NWSSLGMPAH PSMLPVSHNA SPPTSSSQYP SLWSVSNGAV TPGSQAAAVS NGLGAQFFRG SPAHYTPLTH PVSAPSSSGS PLYEGAAAAT DIVDSQYDAA AQGRLIASWT PVSPPSM

靶标信息

The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Brachyury protein; Protein T; RP11-459F1.1; T brachyury homolog; T, brachyury homolog; T-box transcription factor T

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基因别名: SAVA; T; TBXT; TFT

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UniProt ID: (Human) O15178

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Entrez Gene ID: (Human) 6862

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RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding transcriptional repressor activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding Rel homology transcription factor

negative regulation of transcription from RNA polymerase II promoter vasculogenesis somitogenesis neural plate morphogenesis neural tube closure heart morphogenesis positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation transcription, DNA-templated signal transduction penetration of zona pellucida mesoderm development mesoderm migration involved in gastrulation positive regulation of cell proliferation anterior/posterior axis specification, embryo notochord formation signal transduction involved in regulation of gene expression BMP signaling pathway post-anal tail morphogenesis embryonic skeletal system development canonical Wnt signaling pathway bone morphogenesis SMAD protein signal transduction determination of heart left/right asymmetry cellular response to retinoic acid primitive streak formation