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TAAR1 Antibody (PA1-41477) in IHC (P)
Immunohistochemical analysis of TAAR1 in paraffin-embedded formalin-fixed mouse brain tissue. Samples were incubated in TAAR1 polyclonal antibody (Product # PA1-41477) using a dilution of 5 µg/mL. Rabbit isotype control (top) and this antibody (bottom).
Product Details
PA1-41477
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Fish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues 200-230 of human TAAR1.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2199863
Target Information
TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC126874; MGC138399; RP11-295F4.9; RTAR1; Snorf33; TaR-1; trace amine receptor 1; Trace amine-associated receptor 1
Gene Aliases: TA1; TAAR1; taR-1; TAR1; TRAR1
UniProt ID: (Human) Q96RJ0, (Rat) Q923Y9, (Mouse) Q923Y8
Entrez Gene ID: (Human) 134864, (Rat) 113914, (Mouse) 111174
G-protein coupled receptor signaling pathway
cAMP biosynthetic process
signal transduction
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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