Invitrogen

TAAR1 Polyclonal Antibody

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TAAR1 Antibody (PA5-95704) in WB

Western blot analysis of TAAR1 in extracts of various cell lines. Samples were incubated with TAAR1 Polyclonal antibody (Product # PA5-95704) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 6 min.

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产品信息

PA5-95704

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TAAR1 (NP_6122001)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.46 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2807506

产品详细信息

Immunogen sequence: TSTDIMLSSA SIFHLSFISI DRYYAVCDPL RYKAKMNILV ICVMIFISWS VPAVFAFGMI FLELNFKGAE EIYYKHVHCR GGCSVFFSKI SGVLTFMTSF Y; Positive Samples: A-549, Rat stomach; Cellular Location: Cell membrane, Multi-pass membrane protein

靶标信息

TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。