Osenses

TAAR6 Polyclonal Antibody

产品信息

OSR00082W-100UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300-1:2,000

免疫组化 (IHC)

1:300-1:2,000

其他PubMed (Misc)

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产品规格

种属反应

Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from mouse TAAR6 conjugated to an immunogenic carrier protein was used as the antigen

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: TAAR6.

靶标信息

Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. Expressed at low abundance in various brain tissues, as well as in fetal liver, but not in the cerebellum or placenta. In the brain, comparable levels of expression in basal ganglia, frontal cortex, substantia nigra, amygdala and hippocampus, highest expression in hippocampus and lowest expression in basal ganglia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

Genomics

Lindemann L,Ebeling M,Kratochwil NA,Bunzow JR,Grandy DK,Hoener MC

Tue Mar 01 00:00:00 UTC 2005

Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.

American journal of human genetics

Duan J,Martinez M,Sanders AR,Hou C,Saitou N,Kitano T,Mowry BJ,Crowe RR,Silverman JM,Levinson DF,Gejman PV

Fri Oct 01 00:00:00 UTC 2004

The DNA sequence and analysis of human chromosome 6.

Nature

Mungall AJ,Palmer SA,Sims SK,Edwards CA,Ashurst JL,Wilming L,Jones MC,Horton R,Hunt SE,Scott CE,Gilbert JG,Clamp ME,Bethel G,Milne S,Ainscough R,Almeida JP,Ambrose KD,Andrews TD,Ashwell RI,Babbage AK,Bagguley CL,Bailey J,Banerjee R,Barker DJ,Barlow KF,Bates K,Beare DM,Beasley H,Beasley O,Bird CP,Blakey S,Bray-Allen S,Brook J,Brown AJ,Brown JY,Burford DC,Burrill W,Burton J,Carder C,Carter NP,Chapman JC,Clark SY,Clark G,Clee CM,Clegg S,Cobley V,Collier RE,Collins JE,Colman LK,Corby NR,Coville GJ,Culley KM,Dhami P,Davies J,Dunn M,Earthrowl ME,Ellington AE,Evans KA,Faulkner L,Francis MD,Frankish A,Frankland J,French L,Garner P,Garnett J,Ghori MJ,Gilby LM,Gillson CJ,Glithero RJ,Grafham DV,Grant M,Gribble S,Griffiths C,Griffiths M,Hall R,Halls KS,Hammond S,Harley JL,Hart EA,Heath PD,Heathcott R,Holmes SJ,Howden PJ,Howe KL,Howell GR,Huckle E,Humphray SJ,Humphries MD,Hunt AR,Johnson CM,Joy AA,Kay M,Keenan SJ,Kimberley AM,King A,Laird GK,Langford C,Lawlor S,Leongamornlert DA,Leversha M,Lloyd CR,Lloyd DM,Loveland JE,Lovell J,Martin S,Mashreghi-Mohammadi M,Maslen GL,Matthews L,McCann OT,McLaren SJ,McLay K,McMurray A,Moore MJ,Mullikin JC,Niblett D,Nickerson T,Novik KL,Oliver K,Overton-Larty EK,Parker A,Patel R,Pearce AV,Peck AI,Phillimore B,Phillips S,Plumb RW,Porter KM,Ramsey Y,Ranby SA,Rice CM,Ross MT,Searle SM,Sehra HK,Sheridan E,Skuce CD,Smith S,Smith M,Spraggon L,Squares SL,Steward CA,Sycamore N,Tamlyn-Hall G,Tester J,Theaker AJ,Thomas DW,Thorpe A,Tracey A,Tromans A,Tubby B,Wall M,Wallis JM,West AP,White SS,Whitehead SL,Whittaker H,Wild A,Willey DJ,Wilmer TE,Wood JM,Wray PW,Wyatt JC,Young L,Younger RM,Bentley DR,Coulson A,Durbin R,Hubbard T,Sulston JE,Dunham I,Rogers J,Beck S

Thu Oct 23 00:00:00 UTC 2003

Trace amines: identification of a family of mammalian G protein-coupled receptors.

Proceedings of the National Academy of Sciences of the United States of America

Borowsky B,Adham N,Jones KA,Raddatz R,Artymyshyn R,Ogozalek KL,Durkin MM,Lakhlani PP,Bonini JA,Pathirana S,Boyle N,Pu X,Kouranova E,Lichtblau H,Ochoa FY,Branchek TA,Gerald C

Tue Jul 31 00:00:00 UTC 2001

生物信息学

蛋白别名: mTaar6; RP11-295F4.3; TaR-4; TaR-6; Trace amine receptor 4; trace amine receptor 6; Trace amine-associated receptor 6; trace-amine-associated receptor 6

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基因别名: Gm228; Ta4; Taar6; taR-6; Tar4; TRAR4

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UniProt ID: (Rat) Q923Y5, (Mouse) Q5QD13

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Entrez Gene ID: (Rat) 294124, (Mouse) 215855

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功能

trace-amine receptor activity signal transducer activity G-protein coupled receptor activity G-protein coupled amine receptor activity G-protein coupled receptor

参与通路

G-protein coupled receptor signaling pathway signal transduction sensory perception of chemical stimulus positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway