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TACR2 Antibody (PA5-91934) in WB
Western blot analysis of TACR2 in extracts of various cell lines. Samples were incubated with TACR2 Polyclonal antibody (Product # PA5-91934) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-91934
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 319-398 of human TACR2 (NP_0010482)
Conjugate
Form
Liquid
Concentration
2.78 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806333
Product Specific Information
Immunogen sequence: RLAFRCCPWV TPTKEDKLEL TPTTSLSTRV NRCHTKETLF MAGDTAPSEA TSGEAGRPQD GSGLWFGYGL LAPTKTHVEI; Positive Samples: SGC-7901, A-549; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurokinin 2 receptor; Neurokinin A receptor; NK-2 receptor; NK-2R; NK2; seven transmembrane helix receptor; SK receptor; SKR; substance K receptor; Substance-K receptor; Tachykinin receptor 2
Gene Aliases: NK2R; NKNAR; SKR; TAC2R; TACR2
UniProt ID: (Human) P21452
Entrez Gene ID: (Human) 6865
muscle contraction
cell surface receptor signaling pathway
tachykinin receptor signaling pathway
chemical synaptic transmission
excretion
positive regulation of acetylcholine secretion, neurotransmission
intestine smooth muscle contraction
negative regulation of luteinizing hormone secretion
operant conditioning
positive regulation of vascular permeability
positive regulation of smooth muscle contraction
response to electrical stimulus
prolactin secretion
positive regulation of uterine smooth muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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