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TAF1 Antibody (PA5-104490) in ICC/IF
Immunofluorescent analysis of TAF1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and TAF1 polyclonal antibody (Product # PA5-104490) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-104490
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAF1(Accession P21675), corresponding to amino acid residues R1146-R1196.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853791
产品详细信息
Antibody detects endogenous levels of total TAF1.
靶标信息
3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; p250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform; TATA box binding protein associated factor 1; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; Transcription initiation factor TFIID subunit 1
基因别名: AU015687; B430306D02Rik; BA2R; Ccg-1; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; RGD1562050; TAF(II)250; TAF1; TAF2A; TAFII-250; TAFII250; XDP
UniProt ID: (Human) P21675, (Mouse) Q80UV9
Entrez Gene ID: (Human) 6872, (Mouse) 270627, (Rat) 317256
p53 binding
transcription coactivator activity
histone acetyltransferase activity
protein serine/threonine kinase activity
protein binding
ATP binding
transcription factor binding
TBP-class protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
lysine-acetylated histone binding
nucleotide binding
DNA binding
kinase activity
transferase activity
transferase activity, transferring acyl groups
molecular_function
general transcription factor
DNA-templated transcription, initiation
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
cellular response to DNA damage stimulus
cell cycle
viral process
histone acetylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
regulation of signal transduction by p53 class mediator
transcription, DNA-templated
regulation of transcription, DNA-templated
phosphorylation
response to drug
