Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 9
TAF7 Antibody (PA5-114783) in ICC/IF
Immunocytochemistry analysis of TAF7 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114783). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-114783
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TAF7(Accession Q15545), corresponding to amino acid residues R180-S230.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899419
产品详细信息
Antibody detects endogenous levels of total TAF7.
靶标信息
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: RNA polymerase II TBP-associated factor subunit F; TAF(II)55; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55 kDa; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; TAFII-55; TATA box binding protein (TBP) associated factor, RNA polymerase II, F, 55 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD; TATA box binding protein associated factor 7; TBP-associated factor F; transcription factor IID subunit TAFII55; Transcription initiation factor TFIID 55 kDa subunit; Transcription initiation factor TFIID subunit 7; transcription initiation factor TFIID, 55 kDa subunit
基因别名: 55kDa; AI607308; BB007175; TAF2F; TAF7; TAFII55
UniProt ID: (Human) Q15545, (Mouse) Q9R1C0
Entrez Gene ID: (Human) 6879, (Rat) 307485, (Mouse) 24074
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
histone acetyltransferase binding
vitamin D receptor binding
transcription regulatory region DNA binding
thyroid hormone receptor binding
molecular_function
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
spermine transport
DNA-templated transcription, initiation
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
negative regulation of protein kinase activity
intracellular estrogen receptor signaling pathway
negative regulation of histone acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
regulation of transcription from RNA polymerase II promoter
biological_process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of nucleic acid-templated transcription
