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TAL1 Antibody (PA5-117522) in WB
Western Blot analysis of TAL1 using TAL1 Polyclonal Antibody (Product # PA5-117522) at 3 µg/mL. Positive WB detected in: Zebrafish tissue 20 µg, 10 µg. Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 36, 23 kDa. Observed band size: 36 kDa.
Product Details
PA5-117522
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Zebrafish T-cell acute lymphocytic leukemia protein 1 homolog protein (1-324aa)
Conjugate
Form
Liquid
Concentration
2.56 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2902151
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
TAL-1 is a basic helix-loop-helix transcription. It regulates differentiation and survival during hemopoiesis. TAL-1 is also implicated in the genesis of hemopoietic malignancies and it may play an important role in hemopoietic differentiation. It serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. TAL-1 is know to bind to the LIM domain containing protein Rhombotin-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: basic helix-loop-helix transcription factor; HGNC:11556; Stem cell protein; stem-cell leukemia hematopoietic transcription factor; T-cell acute lymphocytic leukemia protein 1 homolog; TAL-1; transcription factor; zSCL
Gene Aliases: scl; SCL-alpha; SCL-beta; scl/tal1; si:ch211-135j1.3; tal-1; tal1; zgc:85605
UniProt ID: (Zebrafish) O93507
Entrez Gene ID: (Zebrafish) 30766
angiogenesis
blood vessel development
vasculogenesis
heart morphogenesis
endocardium morphogenesis
regulation of transcription from RNA polymerase II promoter
multicellular organism development
heart development
stem cell population maintenance
hemopoiesis
myeloid cell differentiation
cell differentiation
erythrocyte differentiation
thyroid gland development
embryonic heart tube development
embryonic hemopoiesis
positive regulation of endothelial cell differentiation
lateral mesoderm development
nucleate erythrocyte development
artery morphogenesis
endocardium formation
primitive hemopoiesis
definitive hemopoiesis
hemangioblast cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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