Invitrogen

TAS1R2 Polyclonal Antibody

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TAS1R2 Antibody (PA5-99935) in WB

Western blot analysis of TAS1R2 in extracts from RAW264.7 cells (serum starvation treatment). Samples were incubated with TAS1R2 polyclonal antibody (Product # PA5-99935). The lane on the left was treated with blocking peptide.

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产品信息

PA5-99935

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（冰冻） (IHC (F))

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human TAS1R2(Accession Q8TE23), corresponding to amino acid residues R226-S276.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2818868

产品详细信息

Antibody detects endogenous levels of total TAS1R2.

靶标信息

Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. Expressed mainly in circumvallate and foliate taste papillae.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Single-cell transcriptomics uncovers the differentiation of a subset of murine esophageal progenitors into taste buds in vivo.

Science advances

Vercauteren Drubbel A,Beck B

PA5-99935 was used in Immunohistochemistry (Frozen) to characterize cervical esophagus epithelium will enable a better understanding of esophageal progenitor potency and insights into the mechanisms involved in the development of taste buds.

Fri Mar 10 00:00:00 UTC 2023

生物信息学

蛋白别名: aldehyde dehydrogenase 4 family, member A1; candidate taste receptor T1R2; G protein-coupled receptor 71; G-protein coupled receptor 71; GPCRB4; Sweet taste receptor T1R2; taste receptor TR2; Taste receptor type 1 member 2; taste receptor, type 1, member 2; TS1R2

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基因别名: Aldh4a1; GPR71; T1R2; TAS1R2; TR2

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UniProt ID: (Human) Q8TE23, (Mouse) Q925I4, (Rat) Q9Z0R7

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Entrez Gene ID: (Human) 80834, (Mouse) 83770, (Rat) 100270683

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功能

G-protein coupled receptor activity taste receptor activity sweet taste receptor activity protein heterodimerization activity signal transducer activity protein binding G-protein coupled receptor

参与通路

detection of chemical stimulus involved in sensory perception of sweet taste G-protein coupled receptor signaling pathway positive regulation of cytokinesis sensory perception of sweet taste signal transduction response to stimulus sensory perception of taste