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Product Details
PA5-58836
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAZ. Recombinant protein control fragment (Product #RP-95183).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648244
Product Specific Information
Immunogen sequence: WHVGMNDVLP NSPPYFPRFG QKITVLIGKP FSALPVLERL RAENKSAVEM RKALTDFIQE EFQHLKTQAE QLHNHLQP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27390; HGNC:11577; OTTHUMP00000061673; Protein G4.5; Tafazzin; Taz; XAP-2; XX-FW83563B9.3
Gene Aliases: BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; TAFAZZIN; TAZ; Taz1
UniProt ID: (Human) Q16635
Entrez Gene ID: (Human) 6901
muscle contraction
heart development
skeletal muscle tissue development
hemopoiesis
cardiolipin biosynthetic process
mitochondrial respiratory chain complex I assembly
cardiolipin acyl-chain remodeling
cristae formation
mitochondrial ATP synthesis coupled electron transport
cardiac muscle tissue development
cardiac muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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