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TBP Antibody (49-1036) in ChIP-seq
ChIP was performed with 5 µg of the anti-TBP antibody (Product # 49-1036) on sheared chromatin from 1 million HeLaS3 cells. The IP’d DNA was analysed by QPCR with optimized PCR primer pairs for the promoters of the active GAPDH and c-fos genes, used as positive control targets, and for a region 1 kb upstream of the GAPDH promoter and the coding region of the inactive MB gene, used as negative control targets (figure A). The IP’d DNA was subsequently analysed with an Illumina Genome Analyzer. Library preparation, cluster generation and sequ... View More
产品信息
49-1036
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
抗原
Raised against the amino-terminal domain of human TBP.
偶联物
形式
Liquid
浓度
8 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
PBS
内含物
<0.1% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Dry ice
RRID
AB_2533885
靶标信息
RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA, RAC1, and CDC42.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC117320; MGC126054; MGC126055; RP1-191N21.3; TATA box binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; tata-box-binding; TATA-box-binding protein; TFIID core protein; Transcription initiation factor TFIID TBP subunit
基因别名: GTF2D; GTF2D1; HDL4; SCA17; TBP; TF2D; TFIID
UniProt ID: (Human) P20226, (Mouse) P29037
Entrez Gene ID: (Human) 6908, (Mouse) 21374
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II repressing transcription factor binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
enzyme binding
transcription regulatory region DNA binding
repressing transcription factor binding
DNA binding
general transcription factor
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
transcription from RNA polymerase III promoter
spermatogenesis
viral process
snRNA transcription from RNA polymerase II promoter
positive regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
regulation of signal transduction by p53 class mediator
transcription, DNA-templated
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
