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TBX15/TBX18 Antibody (PA5-103258) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded TBX15/TBX18 in rat brain tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with TBX15/TBX18 polyclonal antibody (Product # PA5-103258) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-103258
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TBX18(Accession O95935), corresponding to amino acid residues P170-P220.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852620
产品详细信息
Antibody detects endogenous levels of total TBX15/18.
靶标信息
T-box transcription factors are a group of phylogenetically conserved genes that contain a uniquely defining DNA-binding domain, the T-box domain. These genes are believed to be involved in the regulation of development processes. In mouse embryo development, Tbx15 is expressed at the beginning of day 9.5, primarily in the craniofacial region and in the developing limbs. Twelve human T-box genes have been isolated so far. TBX 18 has been reported to be involved in numerous development processes and to act as an antiapoptotic factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: droopy ear; MmTBx8; T-box 14; T-box protein 14; T-box protein 15; T-box protein 18; T-box transcription factor TBX14; T-box transcription factor TBX15; T-box transcription factor TBX18
基因别名: 2810012F10Rik; 2810404D13Rik; CAKUT2; de; TBX14; TBX15; TBX18; Tbx8
UniProt ID: (Human) Q96SF7, (Human) O95935, (Mouse) O70306, (Mouse) Q9EPZ6
Entrez Gene ID: (Human) 6913, (Human) 9096, (Mouse) 21384, (Rat) 295315, (Rat) 315870, (Mouse) 76365
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription corepressor activity
protein binding
protein homodimerization activity
protein heterodimerization activity
transcription regulatory region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
DNA binding
RNA polymerase II transcription factor binding
molecular_function
Rel homology transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
embryonic cranial skeleton morphogenesis
negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
renal system development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
somitogenesis
positive regulation of mesenchymal cell proliferation
sinoatrial node development
sensory perception of sound
biological_process
anterior/posterior axis specification
morphogenesis of embryonic epithelium
positive regulation of cell-cell adhesion
cell differentiation
anatomical structure formation involved in morphogenesis
positive regulation of epithelial cell proliferation
smooth muscle cell differentiation
ureter development
cochlea morphogenesis
positive regulation of mesenchymal cell proliferation involved in ureter development
multicellular organism development
