Invitrogen

TBX2 Polyclonal Antibody

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TBX2 Antibody in Western Blot (WB)

TBX2 Antibody in Western Blot (WB)

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TBX2 Antibody (PA5-40713) in WB

Western blot analysis of human muscle cells using an anti-TBX2 polyclonal antibody (Product # PA5-40713).

TBX2 Antibody in Western Blot (WB)

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TBX2 Antibody in Western Blot (WB) — Western blot analysis of human muscle cells using an anti-TBX2 polyclonal antibody (Product # PA5-40713).

产品信息

PA5-40713

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human TBX2

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2607957

产品详细信息

Peptide sequence: AEIAQAEEQA RKRQEEREKE AAEQAERSQS SIVPEEEQAA NKGEEKKDDE

Sequence homology: Cow: 92%; Dog: 85%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 77%; Pig: 92%; Rabbit: 92%; Rat: 85%

靶标信息

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: FLJ10169; T-box protein 2; T-box transcription factor TBX2

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基因别名: TBX2

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UniProt ID: (Human) Q13207

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Entrez Gene ID: (Human) 6909

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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding protein binding sequence-specific DNA binding Rel homology transcription factor

negative regulation of transcription from RNA polymerase II promoter heart looping outflow tract septum morphogenesis outflow tract morphogenesis endocardial cushion morphogenesis regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation transcription, DNA-templated Notch signaling pathway muscle cell fate determination cell aging regulation of heart contraction positive regulation of cell proliferation embryonic heart tube development aorta morphogenesis atrioventricular canal development embryonic digit morphogenesis negative regulation of transcription, DNA-templated embryonic camera-type eye morphogenesis cardiac muscle tissue development palate development positive regulation of cardiac muscle cell proliferation pharynx development developmental growth involved in morphogenesis mammary placode formation cellular senescence negative regulation of heart looping negative regulation of cardiac chamber formation