Invitrogen

TBX5 Monoclonal Antibody (7B11)

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抗体检测数据 (1)

TBX5 Antibody in Western Blot (WB)

TBX5 Antibody in Western Blot (WB)

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TBX5 Antibody (MA5-15526) in WB

Western blot analysis of TBX5 using TBX5 monoclonal antibody (Product # MA5-15526) in HepG2 cell lysate (1).

TBX5 Antibody in Western Blot (WB)

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TBX5 Antibody in Western Blot (WB) — Western blot analysis of TBX5 using TBX5 monoclonal antibody (Product # MA5-15526) in HepG2 cell lysate (1).

产品信息

MA5-15526

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

酶联免疫吸附实验 (ELISA)

1:10,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

7B11

抗原

Purified recombinant fragment of TBX5 expressed in E. Coli.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

ascites

内含物

0.03% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_10977942

产品详细信息

MA5-15526 targets TBX5 in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15526 immunogen is purified recombinant fragment of TBX5 expressed in E. Coli.

MA5-15526 detects TBX5 which has a predicted molecular weight of approximately 53kDa.

靶标信息

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: T-box protein 5; T-box transcription factor TBX5

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基因别名: HOS; TBX5

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UniProt ID: (Human) Q99593

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Entrez Gene ID: (Human) 6910

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RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding sequence-specific DNA binding

morphogenesis of an epithelium bundle of His development atrioventricular valve morphogenesis endocardial cushion development cardiac left ventricle formation ventricular septum development transcription initiation from RNA polymerase II promoter cell-cell signaling pattern specification process heart development negative regulation of cell proliferation negative regulation of epithelial to mesenchymal transition lung development embryonic limb morphogenesis negative regulation of cell migration embryonic forelimb morphogenesis forelimb morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of cardioblast differentiation cardiac muscle cell differentiation pericardium development negative regulation of cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation transdifferentiation atrial septum morphogenesis cell migration involved in coronary vasculogenesis positive regulation of secondary heart field cardioblast proliferation regulation of execution phase of apoptosis