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产品信息
H00006911-M16
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3F11
抗原
TBX6 (NP_004599, 102 a.a. approximately 200 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: KEFSSVGTEM IITKAGRRMF PACRVSVTGL DPEARYLFLL DVIPVDGARY RWQGRRWEPS GKAEPRLPDR VYIHPDSPAT GAHWMRQPVS FHRVKLTNS*
靶标信息
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: T-box protein 6; T-box transcription factor TBX6
基因别名: SCDO5; TBX6
UniProt ID: (Human) O95947
Entrez Gene ID: (Human) 6911
RNA polymerase II transcription factor binding
RNA polymerase II activating transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
Rel homology transcription factor
negative regulation of transcription from RNA polymerase II promoter
mesoderm formation
cell fate specification
transcription, DNA-templated
mesoderm development
anatomical structure morphogenesis
negative regulation of neuron projection development
negative regulation of neuron maturation
signal transduction involved in regulation of gene expression
somite rostral/caudal axis specification
positive regulation of transcription from RNA polymerase II promoter
