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TC10 Antibody (MA5-37999) in IHC (P)
Immunohistochemistry analysis of TC10 in paraffin-embedded rat spleen. Samples were incubated with TC10 Monoclonal antibody (Product # MA5-37999) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
MA5-37999
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC2309
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 100-205 of human TC10/RHOQ (P17081)
偶联物
形式
Liquid
浓度
1.19 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897917
产品详细信息
Positive Samples: 293T, A-549, 22Rv1, Mouse heart, Rat heart
Immunogen sequence: KEEWVPELKE YAPNVPFLLI GTQIDLRDDP KTLARLNDMK EKPICVEQGQ KLAKEIGACC YVECSALTQK GLKTVFDEAI IAILTPKKHT VKKRIGSRCI NCCLIT
靶标信息
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis secretory protein Li 42; ras homolog gene family, member Q; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; Rho-related GTP-binding protein RhoQ; small GTPase Tc10
基因别名: ARHQ; HEL-S-42; RASL7A; RHOQ; TC10; TC10A
UniProt ID: (Human) P17081, (Mouse) Q8R527, (Rat) Q9JJL4
Entrez Gene ID: (Human) 23433, (Mouse) 104215, (Rat) 85428
small GTPase mediated signal transduction
insulin receptor signaling pathway
regulation of cell shape
cortical actin cytoskeleton organization
cellular response to insulin stimulus
regulation of actin cytoskeleton organization
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
positive regulation of glucose import
regulation of small GTPase mediated signal transduction
positive regulation of filopodium assembly
negative regulation of establishment of protein localization to plasma membrane
actin cytoskeleton organization
negative regulation of glucose import
metabolic process
