Invitrogen

TCF3/TCF4 Monoclonal Antibody (6F12-3)

产品信息

MA1-25418

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-4 µg/mL

免疫组化（石蜡） (IHC (P))

Assay-dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

6F12-3

抗原

His-tagged fusion protein corresponding to residues 31-331 of human TCF4.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.53 mg/mL

纯化类型

Protein G

保存液

TBS, pH 7.4, with 30% glycerol

内含物

0.08% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_795485

产品详细信息

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with b catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: bHLHb19; bHLHb21; Class A helix-loop-helix transcription factor ME2; Class B basic helix-loop-helix protein 19; Class B basic helix-loop-helix protein 21; helix-loop-helix protein HE47; Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; Immunoglobulin transcription factor 2; immunoglobulin transcription factor-2; ITF-1; ITF-2; Kappa-E2-binding factor; MITF-2; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; SEF-2; SL3-3 enhancer factor 2; TCF-3; TCF-4; Transcription factor 3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; Transcription factor 4; Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2); transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R; Transcription factor A1; Transcription factor E2-alpha; transcription factor E2a; Transcription factor ITF-1; VDR interacting repressor; vitamin D receptor-interacting repressor

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基因别名: 5730422P05Rik; A1; AA408400; AGM8; ALF2; ASP-I2; AW209082; BHLHB19; BHLHB21; E12; E12/E47; E2-2; E2.2; E2A; E47; FECD3; ITF-2; ITF-2b; ITF1; ITF2; ME2; MITF-2A; MITF-2B; Pan1; Pan2; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-3; TCF-4; TCF3; TCF4; Tcfe2a; TFE; VDIR