Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-28200
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 117 and 417 of Human TCP1 zeta
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545676
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain.
Predicted reactivity: Mouse (95%), Rat (95%), Zebrafish (85%), Xenopus laevis (85%), Rabbit (96%), Chicken (89%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma, delta, epsilon, zeta, eta and theta, each encoded by a different gene. Two zeta subunits have been described: TCP-1 zeta (also designated TCP-1 zeta1) and TCP-1 zeta2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: acute morphine dependence related protein 2; Acute morphine dependence-related protein 2; amino acid transport defect-complementing; CCT zeta-1; CCT zeta1; CCT- zeta-1; CCT- zeta1; CCT-zeta-1; Chaperonin containing T-complex polypeptide 1 subunit 6A; chaperonin containing T-complex subunit 6; chaperonin containing TCP-1; chaperonin containing TCP1, subunit 6A (zeta 1); chaperonin subunit 6a (zeta); histidine transp; histidine transport regulator 3; HTR3; T-complex protein 1 subunit zeta; T-complex protein 1, zeta subunit; TCP 1 zeta; TCP-1- zeta; TCP-1-zeta; TCP1 zeta; TCP1- zeta; Tcp20
基因别名: CCT-zeta; CCT-zeta-1; CCT6; CCT6A; CCTZ; Cctz-1; Cctz1; HTR3; MoDP-2; TCP-1-zeta; TCP20; TCPZ; TTCP20
UniProt ID: (Human) P40227, (Mouse) P80317
Entrez Gene ID: (Human) 908, (Mouse) 12466
protein folding
positive regulation of telomere maintenance via telomerase
protein stabilization
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
binding of sperm to zona pellucida
toxin transport
