Invitrogen

TEAD1/2/3/4 Recombinant Rabbit Monoclonal Antibody (23GB4680)

TEAD1/2/3/4 Antibody in Immunocytochemistry (ICC/IF)

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TEAD1/2/3/4 Antibody (MA5-52728) in ICC/IF

Immunocytochemistry analysis of TEAD1/2/3/4 in HepG2 cells. Nuclei were stained blue with DAPI; TEAD1/2/3/4 recombinant monoclonal antibody (Product # MA5-52728) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.

TEAD1/2/3/4 Antibody in Western Blot (WB)

TEAD1/2/3/4 Antibody in Flow Cytometry (Flow)

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产品信息

MA5-52728

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫细胞化学 (ICC/IF)

1:1,000

流式细胞分析 (Flow)

1:2,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

23GB4680

抗原

A synthesized peptide derived from human TEAD1+TEAD2+TEAD3+TEAD4 (150-300AA).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

靶标信息

TEAD1, TEAD2, TEAD3, and TEAD4 are members of the TEAD (TEA domain) family of transcription factors. These factors are known to play important roles in various biological processes, including development, cell proliferation, differentiation, and organogenesis.| TEAD1, TEAD2, TEAD3, and TEAD4 exhibit overlapping but also distinct expression patterns and functions. They are involved in diverse cellular processes and have been implicated in the regulation of embryonic development, tissue homeostasis, cell fate determination, and tumor progression. | TEAD proteins are known to interact with various co-factors, including the transcriptional co-activators YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif), which play crucial roles in the Hippo signaling pathway. The interaction between TEAD and YAP/TAZ is essential for the activation of downstream target genes involved in cell proliferation and survival.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DTEF-1; ETF; ETFR-1; NTEF-1; Protein GT-IIC; RTEF-1; RTEF1; TCF-13; TCF13; TEA Domain Family Member 1; TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor); TEA Domain Family Member 2; TEA Domain Family Member 3; TEA Domain Family Member 5; TEA Domain Transcription Factor 1; TEA Domain Transcription Factor 2; TEA Domain Transcription Factor 3; TEAD; TEAD-1; TEAD-2; TEAD-3; TEAD-4; TEAD2; TEAD3; TEAD5; TEF-4; TEF-5; TEF3; TEF4; TEF5; Transcription Factor 13; Transcriptional Enhancer Factor 1; Transcriptional Enhancer Factor 1-Related; Transcriptional Enhancer Factor 5; Transcriptional Enhancer Factor TEF-1; Transcriptional Enhancer Factor TEF-4; Transcriptional Enhancer Factor TEF-5; Transcriptional Enhancer Factor TEF-5 (DTEF-1)

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基因别名: AA; NTEF-1; REF1; TCF-13; TCF13; TEAD-1; TEAD1; TEF-1; TEF1

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UniProt ID: (Human) P28347

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Entrez Gene ID: (Human) 7003, (Rat) 361630

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功能

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter proximal region DNA binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA-binding transcription factor

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